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. 2020 Aug 21;23(4):654–661. doi: 10.1093/ntr/ntaa160

Table 3.

Impact of Type of Smoker Vaping Most Assists in Quitting Smoking by 2100

Vaping does not increase smoking initiation Vaping increases smoking initiation by 10%
Group of smokers most benefiting from vaping-related cessation rate increase Annual cessation rate increase due to vaping (%) Life-years saved (LYS) (millions) LYS as % of life-years lost due (LYL) to smoking in scenario in which e-cigarettes never existed E-quitters (millions) LYS (millions) LYS as % of LYL due to smoking in scenario in which e-cigarettes never existed E-quitters (millions)
Smokers with greatest difficulty quitting otherwise 10 7.1 2.3 4.6 4.7 1.6 4.8
25 15.8 5.2 10.1 13.6 4.5 10.5
50 26.3 8.6 16.5 24.4 8.0 17.2
100 39.1 12.8 24.3 37.6 12.3 25.4
All smokers benefit equally 10 4.9 1.6 3.9 2.5 0.8 4.1
25 11.5 3.8 9.0 9.2 3.0 9.4
50 20.5 6.7 15.9 18.5 6.1 16.6
100 33.8 11.1 25.7 32.1 10.5 26.9
Smokers with least difficulty quitting otherwise 10 4.0 1.3 3.5 1.5 0.5 3.7
25 9.1 3.0 8.0 6.8 2.2 8.3
50 15.9 5.2 13.8 13.7 4.5 14.4
100 25.1 8.2 21.5 23.1 7.6 22.5

Assumptions: (1) Risk of vaping compared to smoking = 10%. (2) The background smoking cessation rate does not vary by the age of the smoker.