. 2006 Mar;27(3):560–572.

Table 2:

Absolute concentrations and concentration ratios of untreated pediatric brain tumors

	Medulloblastoma	Anaplastic Astrocytoma/Astrocytoma	Pilocytic Astrocytoma	Anaplastic Ependymoma/Ependymoma	Choroid Plexus Papilloma	Choroid Plexus Carcinoma	Pineal Germinoma	All Tumors
Subjects	14	8	17	9	3	3	6	60
Absolute concentrations (mmol/kg tissue)
[NAA]	0.9 ± 0.8	2.3 ± 1.5	1.9 ± 0.8	0.2 ± 0.4^****	2.4 ± 1.3	0.2 ± 0.1^*****	1.3 ± 1.1	1.3 ± 1.1
[Cr]	4.7 ± 1.7	6.2 ± 2.4	1.0 ± 0.8^*****	5.3 ± 3.1	1.3 ± 0.7^*	1.2 ± 0.7^*	3.1 ± 0.9	3.5 ± 2.6
[tCho]	5.1 ± 1.5^***	3.9 ± 3.1	2.2 ± 1.1^*	3.2 ± 1.5	1.8 ± 0.3^***	5.1 ± 2.1	2.2 ± 0.5^*	3.4 ± 2.0
[mI]	7.4 ± 4.0	12.3 ± 5.3	3.8 ± 2.1^*****	13.1 ± 5.7	20.4 ± 3.7^*	4.1 ± 2.0	5.2 ± 1.1^*	8.2 ± 5.8
[Gln]	6.3 ± 3.5	9.51 ± 4.1	6.4 ± 3.2	8.4 ± 3.9	2.6 ± 0.6^****	2.6 ± 1.5	4.4 ± 2.6	6.5 ± 3.7
[Glu]	7.5 ± 4.0	4.8 ± 2.9	3.3 ± 1.8^*	2.9 ± 3.2	4.2 ± 2.4	2.7 ± 1.6	8.7 ± 2.7	5.0 ± 3.5
[Glx]^†	13.8 ± 5.2	14.4 ± 4.5	9.7 ± 3.5	11.3 ± 4.4	6.8 ± 2.0	5.4 ± 0.9^****	13.1 ± 3.1	11.5 ± 4.7
[Tau]	5.8 ± 2.3^****	1.7 ± 1.1	0.4 ± 0.6^*****	1.5 ± 1.1	0.8 ± 0.9	2.5 ± 0.6	3.0 ± 1.3	2.3 ± 2.5
[Glc]	1.0 ± 0.8	2.2 ± 1.1	2.5 ± 1.8	0.8 ± 0.7	1.6 ± 0.8	3.4 ± 2.6	0.9 ± 1.0	1.7 ± 1.5
[Lac]	3.6 ± 1.6	2.8 ± 3.9	4.3 ± 2.2	2.1 ± 2.1	0.6 ± 0.5^**	1.5 ± 1.4	0.9 ± 1.6	3.0 ± 2.5
[sI]	0.2 ± 0.2	0.5 ± 0.5	0.2 ± 0.3	0.3 ± 0.3	0.9 ± 0.2	0.0 ± 0.1^***	0.3 ± 0.3	0.3 ± 0.3
[Ala]	2.7 ± 1.2^*	0.9 ± 0.9	1.4 ± 0.7	1.7 ± 1.0	1.0 ± 0.7	0.9 ± 1.0	2.0 ± 0.9	1.7 ± 1.1
[Gua]	3.7 ± 1.1^*	1.5 ± 0.5^****	2.6 ± 1.0	2.4 ± 1.0	3.0 ± 1.0	3.1 ± 0.4	3.7 ± 1.1	2.8 ± 1.2
LipMM09^‡	16.7 ± 9.7	7.0 ± 2.6^**	11.4 ± 5.2	14.5 ± 6.8	4.4 ± 1.6^**	12.5 ± 7.5	12.0 ± 5.4	12.3 ± 7.2
LipMM13^‡	64.3 ± 73.2	15.9 ± 13.4^*	21.8 ± 16.1	49.6 ± 31.4	8.3 ± 2.4^****	61.8 ± 73.9	63.4 ± 53.9	40.6 ± 47.9
[NAA]/[tCho]	0.2 ± 0.2^***	0.9 ± 0.9	0.9 ± 0.4^**	0.1 ± 0.2^***	1.3 ± 0.5	0.1 ± 0.0^*****	0.6 ± 0.5	0.6 ± 0.6
[Crl]/[tCho]	1.0 ± 0.4	2.1 ± 1.2	0.5 ± 0.3^*****	1.8 ± 0.8	0.7 ± 0.3	0.3 ± 0.2^***	1.5 ± 0.5	1.1 ± 0.8
[mI]/[tCho]	1.5 ± 0.9^**	4.0 ± 2.0	1.8 ± 0.7^*	4.8 ± 2.4	11.9 ± 3.7	0.9 ± 0.6^*	2.5 ± 1.1	3.0 ± 2.8
[Gln]/[tCho]	1.2 ± 0.6^****	2.8 ± 1.0	3.2 ± 1.7	2.9 ± 1.6	1.5 ± 0.5	0.7 ± 0.6	2.0 ± 1.2	2.3 ± 1.5
[Glu]/[tcho]	1.5 ± 0.8	1.8 ± 1.7	1.7 ± 0.9	1.3 ± 1.5	2.3 ± 1.0	0.6 ± 0.3^*	4.0 ± 1.1^*	1.8 ± 1.4
[Glx]/[tCho]	2.8 ± 0.9^***	4.7 ± 2.2	4.8 ± 1.7	4.2 ± 2.6	3.8 ± 0.5	1.2 ± 0.7^*	6.0 ± 0.8^**	4.1 ± 2.0
[Tau]/[tCho]	1.2 ± 0.5^**	0.3 ± 0.3	0.2 ± 0.4^*	0.5 ± 0.3	0.5 ± 0.6	0.6 ± 0.3	1.4 ± 0.6	0.6 ± 0.6
[NAA]/[Cr]	0.2 ± 0.2^**	0.4 ± 0.3	1.8 ± 1.2^**	0.1 ± 0.1^****	1.8 ± 0.4	0.1 ± 0.1^***	0.4 ± 0.3^*	0.7 ± 1.0
[mI]/[Cr]	1.7 ± 0.9^*	2.0 ± 0.5^*	3.6 ± 1.9	2.8 ± 1.4	16.6 ± 6.6	7.0 ± 7.3	1.8 ± 0.5^*	3.5 ± 4.0
[Gln]/[Cr]	1.3 ± 0.7^***	1.8 ± 1.0	5.5 ± 2.5^***	1.7 ±0.7	2.0 ± 1.2	4.1 ± 4.0	1.3 ± 1.0	2.7 ± 2.4
[Glu]/[Cr]	1.9 ± 1.5	0.8 ± 0.5^***	3.5 ± 2.5	0.8 ± 1.0^*	3.1 ± 0.4	2.7 ± 1.0	2.9 ± 0.9	2.2 ± 1.8
[Glx]/[Cr]	3.3 ± 1.6	2.6 ± 1.1^*	9.1 ± 4.6^**	2.5 ± 1.4^*	5.1 ± 1.1	7.0 ± 4.8	4.2 ± 1.1	4.9 ± 3.8
[Tau]/[Cr]	1.3 ± 0.4^*	0.2 ± 0.3^*	0.3 ± 0.4^*	0.3 ± 0.3	0.5 ± 0.9	3.6 ± 2.8	1.2 ± 0.8	0.8 ± 1.1
[Gau]/[Cr]	0.9 ± 0.4	0.3 ± 0.1^****	2.7 ± 2.3	0.6 ± 0.3^*	2.4 ± 0.9	5.1 ± 4.3	1.4 ± 0.5	1.6 ± 1.9
[Glc]/[Cr]	0.2 ± 0.2^*	0.4 ± 0.2	2.4 ± 1.5	0.2 ± 0.2^*	1.5 ± 1.3	6.5 ± 7.9	0.3 ± 0.3	1.2 ± 2.3

Note:—

P < .01,

^**

P < .001,

^***

P < .0001,

^****

P < .00001,

^*****

P< .000001 versus All Other tumors

^†

[Glx] = [Glu] + [Gln].

^‡

Absolute intensity (arbitrary units).