Fig. 2.

Frontal and lateral facial profiles of six affected individuals carrying bi-allelic EIF3F variants. a, b represent P3 at 5y, c P5 at 4m and d, e P5 at 4y 3m, f, g show P9 at 13y and at 17y, respectively, h, i P12 at 2y 8m, j, k P13 at 3y 2m and l, m P15 at 6y 8m. All affected individuals have fairly even palpebral fissures, a pointed nasal tip which is rather prominent for age at lateral view. Note nasal fistula and groove at left lip in P5 before surgery (c), and after correction (d). y = years; m = months