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RNA based therapeutics in clinical trials in lung cancer
| Drug combination | Affected Pathway | References |
|---|---|---|
| Custirsen + gemcitabine + cisplatin | Clusterin | [288] |
| Aprinocarsen + gemcitabine + cisplatin | PKC-a | [300, 303, 304] |
| Imetelstat + bevacizumab | Telomerase | [286] |
| LY2181308 + docetaxel | Survivin | [305] |
| Oblimersen + paclitaxel | Bcl2 | [283] |
| Oblimersen + carboplatin + etoposide | Bcl2 | [285] |
