Table 1:
Summary of patient histories
| Patient no: Age/Sex | Primary Disorder | Type of Transplant | Interval between Transplantation and Symptoms Onset | Neurological Symptoms |
Specimen and Quantity of HHV-6 PCR | Outcome | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Disorientation | Short-term Memory Loss | Coma | Hypopnea | Convulsion | ||||||
| 1:49/F | Acute leukemia | Cord blood stem cell | 27 | + | + | 9000 (CSF) and 3000 (blood*) copies/mL | Improved (remaining disorientation and memory loss) | |||
| 2:41/F | Acute leukemia | (Peripheral blood stem cell) | (979) | + | + | 49,000 copies/mL (CSF) | Improved (remaining disorientation and memory loss) | |||
| 3:55/M | Non-Hodgkin lymphoma | Bone marrow | 22 | + | + | 400,000 copies/mL (blood) | Dead (sepsis) | |||
| 4:52/M | Non-Hodgkin lymphoma | Bone marrow | 14 | + | + | + | 58,000 copies/mL (CSF) | Improved | ||
| 5:36/M | Acute leukemia | Bone marrow | 19 | + | + | + | + | + | 2300 copies/mL (CSF) | Dead (intestinal pneumonitis) |
| 6:37/F | Acute leukemia | Bone marrow | 17 | + | + | + | 3000 copies/mL (CSF) | Dead (liver failure) | ||
Note:—HHV-6 indicates human herpesvirus 6; PCR; polymerase chain reaction.
Peripheral blood.