Table 2.

Patient characteristics (US group) according to tumor size estimation and discordance between US and histology

	Overestimation US – Histol. > 10 mm	Difference US – Histol. ≤10 mm	Underestimation US – Histol. > 10 mm	Unknown	Total
Number of patients (% of total)	60 (10.20)	407 (69.22)	93 (15.82)	28 (4.76)	588 (100.00)
Age at initial visit [years]
Mean	53.13	51.16	52.89	52.46	51.70
SD	12.49	11.71	9.54	10.84	11.44
Median	50.00	51.00	53.00	50.00	51.00
Min	31.00	21.00	32.00	30.00	21.00
Max	75.00	77.00	78.00	74.00	78.00
N.d.	0	2	0	0	2
Central grade, N (%)
1	0 (0.00)	8 (80.00)	2 (20.00)	0 (0.00)	10 (100.00)
2	32 (13.60)	168 (71.19)	27 (11.44)	9 (3.81)	236 (100.00)
3	28 (8.26)	228 (67.26)	64 (18.88)	19 (5.60)	339 (100.00)
N.d.	0 (0.00)	3 (100.00)	0 (0.00)	0 (0.00)	3 (100.00)
Clinical baseline characteristics, N (%)
cT
1	15 (6.36)	196 (83.05)	14 (5.93)	11 (46.61)	236 (100.00)
2	35 (11.11)	196 (62.22)	68 (21.59)	16 (5.08)	315 (100.00)
3	7 (23.33)	12 (40.00)	10 (33.33)	1 (3.33)	30 (100.00)
4	3 (42.86)	3 (42.86)	1 (14.29)	0 (0.00)	7 (100.00)
cN
0	33 (7.97)	304 (73.43)	58 (14.01)	19 (4.59)	414 (100.00)
1	25 (16.23)	93 (60.39)	30 (19.48)	6 (3.90)	154 (100.00)
2	2 (10.53)	9 (47.37)	5 (26.32)	3 (15.79)	19 (100.00)
3	0 (0.00)	1 (100.00)	0 (0.00)	0 (0.00)	1 (100.00)
Menopausal status, N (%)
Premenopausal	31 (10.99)	199 (70.57)	38 (13.48)	14 (4.96)	282 (100.00)
Postmenopausal	28 (10.07)	189 (67.99)	49 (17.63)	12 (4.32)	278 (100.00)
Unknown/unclear	1 (3.57)	19 (67.86)	6 (21.43)	2 (7.14)	28 (100.00)
BC subtype, N (%)
HR+/HER2+	28 (10.98)	187 (73.33)	31 (12.16)	9 (3.53)	255 (100.00)
HR−/HER2−	26 (10.44)	166 (66.67)	45 (18.07)	12 (4.82)	249 (100.00)
HR−/HER2+	6 (7.14)	54 (64.29)	17 (20.24)	7 (8.33)	84 (100.00)