Table 4. Comparison of characteristics between survivors and non-survivors after anti-viral therapy.
| All patients (N = 479) | Survivors (N = 457) | Non-survivors (N = 22) | P value | |
|---|---|---|---|---|
| Age ≥ 75 | 208 / 479 (43.4) | 197 / 457 (43.1) | 11 / 22 (50) | 0.677 |
| Male | 209 / 479 (43.6) | 198 / 457 (43.3) | 11 / 22 (50) | 0.692 |
| SVR(+) | 476 / 479 (99.4) | 454 / 457 (99.3) | 22 / 22 (100) | 1.000 |
| Cirrhosis | 217 / 479 (45.3) | 199 / 457 (43.5) | 18 / 22 (81.8) | 0.001 |
| Cancer | 70 / 479 (14.6) | 62 / 457 (13.6) | 8 / 22 (36.4) | 0.008 |
| Diabetes mellitus | 89 / 479 (18.6) | 85 / 457 (18.6) | 4 / 22 (18.2) | 1.000 |
| Hypertension | 146 / 479 (30.5) | 140 / 457 (30.6) | 6 / 22 (27.3) | 0.922 |
| Child–Pugh Classification for cirrhotic patients, n /N(%) | 0.506 | |||
| A | 209/217 (96.3) | 192/199 (96.5) | 17/18 (94.4) | |
| B | 8/217 (3.7) | 7/177 (3.5) | 1/18(5.6) | |
| Ascites | 0.009 | |||
| None | 463 / 479 (96.7) | 444 / 457 (97.2) | 19 / 22 (86.4) | 0.032 |
| Mild | 14 / 479 (2.9) | 11 / 457 (2.4) | 3 / 22 (13.6) | 0.022 |
| Moderate | 2 / 479 (0.4) | 2 / 457 (0.4) | 0 / 22 | 1.000 |
| FIB4 | 3.89 (2.64–6.03) | 3.87 (2.64–5.91) | 6 (3.44–8.86) | 0.019 |
| Hepatitis B | 26 / 479 (5.4) | 24 / 457 (5.3) | 2 / 22 (9.1) | 0.338 |
| HCV RNA, IU/mL, log10 | 5.78 (4.81–6.28) | 5.8 (4.82–6.29) | 5.68 (4.34–6.09) | 0.244 |
| CHD | 1 / 479 (0.2) | 1 / 457 (0.2) | 0 / 220 | 1.000 |
| HIV | 6 / 479 (1.3) | 5 / 457 (1.1) | 1 / 22 (4.5) | 0.247 |
| CVA | 13 / 479 (2.7) | 13 / 457 (2.8) | 0 / 220 | 1.000 |
| ESRD | 14 / 479 (2.9) | 14 / 457 (3.1) | 0 / 220 | 1.000 |
| BMI | 23.57 (21.31–26.06) | 23.57 (21.33–26.07) | 23.44 (20.7–25.81) | 0.71 |
| CRE | 0.9 (0.68–1.16) | 0.89 (0.68–1.14) | 1.04 (0.93–1.75) | 0.011 |
| eGFR | 73.53 (54.94–90.11) | 73.98 (55.67–90.34) | 56.62 (38.4–76.08) | 0.025 |
| ALT | 48 (29–83) | 48 (29–83) | 48.5 (30–80) | 0.795 |
| INR | 0.97 (0.92–1.03) | 0.97 (0.92–1.03) | 0.97 (0.94–1.06) | 0.665 |
| BIL | 0.74 (0.58–1.01) | 0.74 (0.58–1) | 0.89 (0.46–1.19) | 0.552 |
| ALB | 3.8 (3.5–4.1) | 3.9 (3.6–4.1) | 3.4 (3.2–3.6) | <0.001 |
| HB | 13 (11.5–14.2) | 13 (11.6–14.3) | 12 (10.3–13.5) | 0.021 |
Notes.
- BMI
- body mass index
- ALT
- alanine aminotransferase
- BIL
- bilirubin
- ALB
- albumin
- CRE
- Creatinine
- INR
- international normalized ratio
- HB
- haemoglobin
- FIB-4
- Fibrosis-4
- CHD
- coronary heart disease
- HIV
- Human immunodeficiency virus
- CVA
- cerebrovascular accident
- HCV
- hepatitis C virus
- eGFR
- estimated Glomerular filtration rate
- SVR
- sustained virologic response