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. 2021 Mar 5;8:586875. doi: 10.3389/fmed.2021.586875

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Copyright © 2021 Levast, Benech, Gasc, Batailler, Senneville, Lustig, Pouderoux, Boutoille, Boucinha, Dauchy, Zeller, Maynard, Cazanave, Le Thi, Josse, Doré, Laurent and Ferry.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation between systemic and mucosal markers of inflammation. (A) Evolution of the plasmatic level of C-reactive protein (CRP) at different time points. (B) Correlation between fecal neopterin and plasmatic CRP; simple linear regression. (C) Principal coordinate analysis of Bray–Curtis distance between patients with each sample colored according to plasmatic CRP level at the end of treatment; permutational multivariate analysis of variance. B, baseline; EOT, end of treatment; FU, follow-up. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.