Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 25;11(9):4351–4362. doi: 10.7150/thno.52436

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

Enhanced delivery efficiency of DiR-exosomes by FUS-BBB opening. (A) Setup of FUS-BBB opening equipment. (B) SEM of microbubbles, scale bar: 1 µm. (C) BBB opening by FUS was indicated by evans blue dye. (D) H&E staining of brain post FUS treatment. (E) In vivo imaging scheme of FUS-BBB opening-assisted brain-targeted delivery of DiR-labeled exosomes. (F) IVIS imaging of brain accumulation of DiR-labeled exosomes after i.v. injection post FUS-BBB opening. (G) Brain accumulation of DiR-labeled exosomes after FUS-BBB opening demonstrated by CLSM pictures of brain slices, scale bar: 100 µm.