Figure 6.

Antitumor effect of combination therapy of TRAIL proteins and Ze-IR700-mediated PDT in mice bearing LS174T tumor grafts. A. Dynamic optical imaging of mice bearing tumor grafts of RFP-expressing LS174T cells treated with TRAIL proteins in combination with or without PDT. B. Representative pictures of mice bearing tumor grafts before and after treatment with combination therapy of IgBD-TRAIL and PDT. C. Growth curves of tumor grafts after treatment with monotherapy or combination therapy of TRAIL proteins and PDT. A single treatment was administered at day 0. The number of mice with tumor eradication (tumor free) is indicated.