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. 2021 Feb 25;11(9):4281–4297. doi: 10.7150/thno.51193

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Antitumor effect of combinational therapy of TRAIL proteins and Ze-IR700-mediated PDT in mice bearing HT29 tumor grafts. A. Uptake of TRAIL proteins by tumor grafts treated with or without PDT. B. Apoptosis induction by monotherapy or combination therapy of TRAIL proteins and PDT in tumor grafts. C. Growth curves of tumor grafts treated with monotherapy or combination therapy of TRAIL proteins and PDT. The number of mice with tumor eradication (tumor free) is indicated. D. Representative optical images of mice bearing tumor grafts during treatment with combination therapy of IgBD-TRAIL and PDT. A single treatment was administered at day 0.