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. 2021 Feb 19;11(9):4061–4077. doi: 10.7150/thno.52558

Figure 2.

Figure 2

GDNP induces miR-375 in MC-38 cells and sorts into exosomes. (A) qRT-PCR for intracellular and exosomal miR-375 levels and AhR expression in MC-38 cells cultured with various concentrations of GDNP for 12 h. (B) qRT-PCR comparison for intracellular vs exosomal levels of miR-375 in MC-38 cells cultured with various concentrations of GDNP. (C) miR-375 levels expression in MC-38 cells cultured with GDNP in a time dependent manner. (D) miR-375 levels expression in FL83B (hepatocyte) cells cultured with GDNP in a dose dependent manner. One-way ANOVA with the Bonferroni correction for multiple comparisons and the Student t test (one tailed) were used to calculate statistical significance (p value *<0.05; **<0.01; ***<0.001).