A 61-year-old man with glioblastoma (grade IV).
A, Axial FLAIR image reveals a large necrotic tumor in the right frontal lobe with a rectangular voxel (8.0 cm3).
B, 1H-MR spectrum obtained at short TE (2000/35) shows increased Cho/Cr ratio (1.5:1), increased Cho/NAA ratio (1.2:1), and markedly increased LL/Cr ratio (3.8:1) at 1.3 ppm.
C, 1H-MR spectrum obtained at intermediate TE (1500/144) shows more increased Cho/Cr ratio of (2.2:1), more increased Cho/NAA ratio (2.1:1), and a smaller inverted lactate peak with smaller lipid peaks at 1.2–1.4 and 0.9 ppm (LL/Cr: 0.9:1). The baseline of the spectrum is noisier than B.