Table 3.
Cox regression analysis of patient survival during the 5-year study period
| Univariate Cox regression | Multivariate Cox regression | |||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age | 1.06 (1.03–1.08) | < 0.001* | 1.03 (1.01–1.05) | 0.001† |
| Male | 0.74 (0.45–1.23) | 0.242 | ||
| eGFR < 45 mL/min/1.73 m2 | 2.90 (1.79–4.70) | < 0.001* | 2.05 (1.31–3.21) | 0.002† |
| Hypertension | 1.37 (0.68–2.76) | 0.379 | ||
| Diabetes mellitus | 0.90 (0.56–1.44) | 0.651 | ||
| Hyperlipidemia | 0.52 (0.32–0.83) | 0.007* | ||
| Coronary artery disease | 2.54 (1.55–4.14) | < 0.001* | 1.98 (1.28–3.06) | 0.002† |
| Atrial fibrillation | 1.89 (1.10–3.23) | 0.021* | ||
| Congestive heart failure | 2.72 (1.56–4.76) | < 0.001* | ||
| Smoking | 1.01 (0.61–1.66) | 0.980 | ||
| TACI | 3.34 (2.06–5.42) | < 0.001* | 2.72 (1.75–4.25) | < 0.001† |
| Pneumonia | 2.54 (1.47–4.40) | 0.001* | ||
| Gastrointestinal bleeding | 2.36 (1.41–3.95) | 0.001* | 1.73 (1.10–2.71) | 0.018† |
HR indicates hazard ratio; CI confidence interval; TACI total anterior circulation infarcts
*P < 0.1 for the univariate Cox regression, and †P < 0.05 for the multivariate Cox regression