Fungal abscess in the frontal lobe of a 39-year-old man with non-Hodgkin lymphoma on treatment.
Axial T2-weighted image (A) shows a well-defined heterointense lesion in the right frontal lobe with an irregular hypointense wall. Hypointense projections attached to the wall are well demonstrated. White arrows show the crenated margin of the fungal wall. Axial T1-weighted image (B) shows a hypointense core with isointense intracavitary projections. Postcontrast axial T1-weighted image (C) shows peripheral enhancement of the wall with no enhancement of intracavitary projections. Note the presence of 2 more enhancing lesions in the right thalamus and right occipital regions, which are better seen in adjoining sections. Diffusion-weighted image (D) shows hyperintensity in the projections with hypointensity in the cavity. On an ADC map (E), intracavitary projections show low ADC (0.46 × 10−3 mm2/s) with high ADC in the cavity (2.22 × 10−3 mm2/s). PMRS (F) obtained with a voxel size of 2 mL shows lactate along with lipid (Lac/Lip, 1.3 ppm). Culture from pus grew Aspergillus flavus.