Fig 6.

A, Sagittal SS-FSE T2-weighted image in a 23-gestational-week-old fetus demonstrates abnormally thin brain stem with kinking at pontomesencephalic junction. Callosal and vermian agenesis was detected by prenatal sonography and is also present on the MR imaging.

B, Axial SS-FSE T2-weighted image demonstrates abnormally thin and homogeneous parenchyma with absent Sylvian fissures. The deep gray nuclei appear small and dysplastic as well.

This constellation of findings led to the prenatal diagnosis of Walker-Warburg syndrome.