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. 2021 Mar 18;2021:9363569. doi: 10.1155/2021/9363569

Table 2.

Baseline differences in secondary cardiac injury biomarkers between COVID-19 survivors and nonsurvivors.

Biomarker Studies Patients Heterogeneity SMD (95% CI) P
Nonsurvivors Survivors Total Model I 2 (%)
CK-MB 2 48 123 171 F 0 0.97 (0.62, 1.32) <0.0001
hs-CRP 5 231 595 826 R 99 2.78 (0.90, 4.65) 0.004
IL-6 3 137 306 443 R 99 3.13 (0.24, 6.03) 0.03
Myoglobin 2 89 240 329 R 99 3.00 (−1.36, 7.36) 0.18

CI, confidence interval; CK-MB, creatine kinase-myocardial bound; CRP, C-reactive protein; F, fixed-effects model; IL-6, interleukin-6; R, random-effects model; SMD, standardized mean difference.