Skip to main content
. 2020 Dec 19;42(6):1727–1741. doi: 10.1002/hbm.25324

TABLE 4.

Mean (SD) functional connectivity and effect sizes of edges in the NBS component (intensity, F ≥ 15) and FDR significant edges

Non‐CUD CUD Cohen's d p BF a
NBS—intensity
R fusiform to R Inf temporal −0.020 (0.082) 0.046 (0.099) 0.750 .00059 c d e f g h 106
R sup parietal to L insula 0.023 (0.094) −0.043 (0.048) −0.793 .00000 c d g 214
R fusiform R to R insula −0.015 (0.074) 0.043 (0.088) 0.750 .00053 c d e f g 107
R sup parietal to R insula b 0.022 (0.068) −0.051 (0.066) −1.078 .00000 c g 180,522
L sup parietal to R insula 0.021 (0.082) −0.051 (0.088) −0.863 .00004 c g 728
NBS—extent
L mid occipital to L lingual −0.022 (0.084) 0.048 (0.115) 0.747 .00104 c d e f g h i 101
L precuneus to L lingual 0.015 (0.096) −0.060 (0.102) −0.756 .00025 c d f g h i 117
L mid occipital to R mid temporal −0.035 (0.128) 0.087 (0.175) 0.851 .00023 c d f g h i 584
L mid occipital to R fusiform −0.039 (0.132) 0.080 (0.183) 0.801 .00053 c d f g h i 244
R mid occipital to R fusiform −0.041 (0.152) 0.092 (0.218) 0.763 .00105 c d f g h i 132
L mid occipital to R cuneus −0.028 (0.107) 0.065 (0.135) 0.798 .00034 c d f g h i 235
L mid occipital to R lingual −0.026 (0.089) 0.055 (0.138) 0.767 .00132 c d f g h i 141
L precuneus to R lingual 0.017 (0.089) −0.051 (0.098) −0.745 .00039 c d f g h i 99
L mid occipital to cuneus −0.027 (0.100) 0.059 (0.126) 0.786 .00040 c d f g h i 191
FDR
L accumbens to R hippocampus −0.019 (0.068) 0.037 (0.072) 0.822 .00008 c g 351
L mid frontal to vermis crus I 0.019 (0.070) −0.041 (0.075) −0.837 .00006 f 457
R sup parietal to R insula b 0.022 (0.068) −0.051 (0.066) −1.078 .00000 g 180,522

Note: Values are standardized residuals.

Abbreviations: BF = Bayes factor.

a

See Supporting information on interpretation of BF and multiple testing.

b

This edge is present in the FDR and NBS‐intensity network.

c

Not significant after controlling for nicotine dependence.

d

Not significant after controlling for drinks/month.

e

Not significant after controlling for SUD.

f

Not significant after controlling for education.

g

Not significant when excluding outliers.

h

Not significant after controlling for DVARS.

i

Not significant after controlling for lifetime AUD.