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. 2021 Mar 4;11(10):4929–4944. doi: 10.7150/thno.55672

Figure 1.

Figure 1

PINT87aa was overexpressed in H2O2-induced senescent HCC cells. (A) Schematic diagram of NR_109851, transcription of LINC-PINT generating linear PINT (linePNT) and circular PINT (circPINT) that could encode the PINT87aa peptide. (B) qRT-PCR detected circPINT and linePINT expression in senescent and proliferating SMMC-7721 and MHCC-97H cells. (C) FISH detected circPINT expression in senescent and proliferating SMMC-7721 and MHCC-97H cells. Scale bars = 15 μm. (D) Western blotting detected PINT87aa expression in senescent and proliferating SMMC-7721 and MHCC-97H cells. *P < 0.05; **P < 0.01; ***P < 0.001; ns P > 0.05.