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. Author manuscript; available in PMC: 2021 Mar 19.
Published in final edited form as: ACS Sens. 2020 May 26;5(6):1707–1716. doi: 10.1021/acssensors.0c00345

Figure 1.

Figure 1.

(a) Schematic illustration of the identification strategy of single AA derivatives through α-HL nanopore. The characteristic signals 1, 2, and 3 are from NITC-Ala, NITC-His, and NITC-Tyr, respectively. (b) Synthetic routes of different AA derivatives. Route i is for PITC/NITC derivatives; route ii is for OPA/NDA derivatives. (c) Translocation events frequency of raw materials and various derivatives through α-HL nanopores under the same experimental condition. Statistical significance is shown between derivatives and corresponding single AA (*: 0.01 < p <0.05; **: 0.001 < p < 0.01; ***: 0.0001 < p < 0.001; and ****: p < 0.0001).