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. 2021 Mar 19;66:103288. doi: 10.1016/j.ebiom.2021.103288

Figure 1.

Figure 1

In vitro antiviral activity. (a) Antiviral activity of itraconazole and hydroxy-itraconazole at different concentrations in the SARS-CoV-2 / VeroE6-eGFP assay system. Green fluorescence indicates cells surviving SARS-CoV-2 infection. Itraconazole was tested in two independent experiments while hydroxy-itraconazole (17-OH-itraconazole) was tested in one experiment. (b) Antiviral activity of azithromycine, hydroxychloroquine and GS-441524 in two independent experiments. (c) Antiviral activity of itraconazole and other azoles different concentrations in the SARS-CoV-2 / VeroE6-eGFP assay system. VC indicates “Virus Control” i.e. infected untreated cultures; CC indicates “Cell Control” i.e. uninfected untreated cultures; GS-441524 is the parent nucleoside of remdesivir.