Figure 1.

Prognostic value of miR-222-3p in human cancer. miR-222-3p expression in different types of human cancer was analyzed from The Cancer Genome Atlas database. Patients were divided into two groups according to the expression levels of miR-222-3p, either lower or higher than the mean value. The Kaplan-Meier analysis method was used for survival analysis using the software GraphPad Prism 7. Log-rank P<0.05 was considered to indicate a statistically significant difference. Considering the mid- and late-stage crossovers, the weighted method of Cramer-von Mises testing was used. (A) Seven types of cancer in which the overall survival of patients was significantly associated with miR-222-3p expression. (B and C) Eleven types of cancer in which the overall survival of patients was not significantly associated with miR-222-3p expression. miR, microRNA.