Table 1.
Characteristics | Patients (n = 23) 36 orbits | Normal controls (n = 15) 15 orbits |
---|---|---|
Sex (number of patients) | ||
Female | 18 | 4 |
Male | 5 | 11 |
Age (years) | ||
Range | 35-73 | 36-56 |
Median | 65 | 46 |
Disease status (number of orbits) | ||
Moderate-to-severe GO | 14 | |
Severe GO | ||
With DON | 12 | |
With severe keratitis | 10 | |
Graves' disease (number of patients) | 23 | |
Median CAS | 2 | |
Thyroidectomy | 7 | |
Median proptosis (mm) | 23 | |
Median IOP (mmHg) | 16 | |
Median BCVA | 0.9 | |
Median fT4 (pmol/L) | 19.4 | |
Median TRAb (U/L) | 12.4 | |
Median aTPO (U/mL) | 89.3 | |
Median aTG (U/mL) | 144 |
Abbreviations: DON: dysthyroid optic neuropathy; CAS: clinical activity score; IOP: intraocular pressure; BCVA: best-corrected visual acuity; fT4: free thyroxine; TRAb: anti-TSHR antibodies; aTPO: antithyroid peroxidase; aTG: antithyroglobulin.