Table 3.
431 Correlation Analysis Between KRASG12C and Clinic Pathological Factors in Patients
KRASG12C-mut n=20 | KRASG12C-wt n=411 | P-value | |
---|---|---|---|
Sex | |||
Male | 12 | 186 | 0.2515 |
Female | 8 | 225 | |
Age | |||
<60 year | 2 | 155 | 0.0151* |
≥60 year | 18 | 256 | |
Stage | |||
I–III | 10 | 105 | 0.0343* |
IV | 10 | 306 | |
Smoking history | |||
Yes | 14 | 154 | 0.0046** |
No | 6 | 257 | |
Brain metastasis | |||
Yes | 3 | 103 | 0.4282 |
No | 17 | 308 | |
PS score | |||
0–1 | 16 | 349 | 0.5266 |
2–3 | 4 | 62 | |
Histology | |||
Adenocarcinoma | 18 | 352 | 0.7526 |
Squamous cell carcinoma | 2 | 59 |
Notes: *P-value <0.05; **P-value <0.01.
Abbreviations: mut, mutation; wt, wild type.