Table 1.
Overview of Silver and Gold Nanoparticles and Their Applications for Gliomas
| NP (and Its Functionalization) | Mean Size (nm) | Application | Ref. |
|---|---|---|---|
| GNPs | 1.9 15 |
Therapeutic radiotherapy | [81] |
| SNPs-PVP | 10 | Radiotherapy-imaging | [8] |
| GNPs-citrate and SNPs-citrate |
15 | Radiotherapy-imaging | [83] |
| GNP-PEG-FAL | 60 | Imaging-targeting and therapy | [93] |
| SNP-PLGA-CTX | 114 | Sensing and therapy | [82] |
| GNS-IR780-PEG | 100 | Imaging | [94] |
| GNPs-U2 aptamer | 60 | Therapy | [79] |
| GNP-miR-182 | 13 | Therapy | [80] |
| GNP-DOX-An | 40 | Delivery-therapy | [87] |
| GNP-AK-citrate GNP-CABT-citrate |
40 | Treatment | [88] |
| GNPs-A&C-R, combined targeting with peptide R8-RGD | 41 | Treatment | [89] |
| GNP-131I-PENPs-CTX | 151 147 |
Imaging and therapy | [95] |
| CD–CS-T7-CD-CS-polyGION-miRNA | 34 | Theranostic | [86] |
| GNP-PP-polyI:C | 13 | Delivery-treatment | [17] |
| GNR-CD133 antibody | 10 x 40 nm | Treatment | [92] |
| GNP-Cis | 7 | Treatment | [90] |
Abbreviations: FAL, Phe-Ala-Leu-Gly-Glu-Ala; PLGA, poly-lactic-co-glycolic acid; CTX, chlorotoxin; DOX, doxorubicin; An, angiopep-2; AK, Ala-Ala-Asn-Cys-Lys; CABT, 2-cyano-6-aminobenzothiazole; PENP, polyethyleneimine; PP, methoxypolyethylene glycol-polyethyleneimine; polyI:C, polyinosinic-polycytidylic acid; Cis, cisplatin; CD–CS-T7-CD-CS-polyGION-miRNA, gold iron oxide nanostars loaded with miR-100 and antimiR-21 and T7 peptide functionalized β-cyclodextrin-chitosan.