Table 7.
The Effect of Leaf Exudate on Body Weight in STZ-Induced Diabetic Mice
| Treatment Group | Weight of Mice | ||||
|---|---|---|---|---|---|
| D0 | D7 | D14 | D21 | % ∆ in BW | |
| (normal) 2% DMSO | 24.06 ± 0.36 | 25.87 ± 0.36 | 26.04 ± 0.52 | 27.84 ± 0.45 | 15.7 |
| (diabetic) 2% DMSO | 23.63 ± 0.48 | 22.60 ± 0.66 | 22.44 ± 0.72 | 22.10 ± 1.34 | −6.47 |
| 100 mg/kg exudate | 24.16 ± 0.49 | 24.04 ± 0.66 | 24.55 ± 0.67 | 25.48 ± 0.52 | 5.46 |
| 200 mg/kg exudate | 24.44 ± 0.71 | 25.36 ± 0.54 | 25.65 ± 0.48 | 26.79 ± 0.65* | 9.62 |
| 400 mg/kg exudate | 24.30 ± 1.33 | 24.66 ± 0.83 | 26.03 ± 0.70* | 27.05 ± 0.94** | 11.32 |
| 2 mg/kg GA | 24.13 ± 1.34 | 24.39 ± 1.17 | 25.90 ± 1.36* | 26.39 ± 1.26* | 9.37 |
Notes: % ∆ in BW: % of change in body weight; data are expressed as mean ± standard error of mean (SEM); n=6; where *significant values at p<0.05 compared with group II, ** significant values at P<0.01 compared with group II.
Abbreviations: DMSO, dimethyl sulfoxide; GA, glibenclamide.