Table 8.

The Effect of Isolates on Body Weight in STZ-Induced Diabetic Mice

Treatment Group	Weight of Mice
	D0	D7	D14	D 21	% ∆ in BW
(normal) 2% DMSO	26.38 ± 0.49	27.79 ± 0.60	29.02 ± 0.54	30.72 ± 0.60	16.45
(diabetic) 2% DMSO	27.17 ± 1.03	25.77 ± 0.89	24.58 ± 0.84	23.86 ± 0.97	−12.18
200 mg/kg Ia	26.52 ± 0.95	26.80 ± 1.06	27.45 ± 1.02	27.83 ± 1.05	4.4
400 mg/kg Ia	25.89 ± 1.15	26.40 ± 1.37	27.74 ± 1.53	28.48 ± 1.30*	10
200 mg/kg Ib	25.52 ± 0.82	26.49 ± 0.72	27.88 ± 0.78	28.78 ± 0.64*	12.77
400 mg/kg Ib	24.01 ± 0.69	25.36 ± 0.78	27.60 ± 0.61	28.92 ± 0.60**.	20.45
200 mg/kg Ic	25.48 ± 0.89	26.52 ± 0.82	27.13 ± 0.84	27.47 ± 0.78	7.8
400 mg/kg Ic	24.96 ± 1.07	25.38 ± 1.30	26.50 ± 1.31	26.65 ± 1.14	6.77
2 mg/kg GA	26.32 ± 0.97	27.97 ± 0.99	29.28 ± 0.98*	30.80 ± 0.89***	17

Notes: Data are expressed as mean ± standard error of mean (SEM); n=6; where *significant values at p<0.05 compared with group II; ** significant values at p<0.01 compared with group II; ***significant values at p<0.001 compared with group II.

Abbreviations: DMSO, dimethyl sulfoxide; GA, glibenclamide; Ia, isolate a; Ib, isolate b; Ic, isolate c; % ∆ in BW, % of change in body weight.