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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Curr Opin Virol. 2020 Oct 30;46:20–26. doi: 10.1016/j.coviro.2020.09.006

Table 1.

Tissue and viral infection models of CD4+ and CD8+TRM-mediated protection

Tissue Location Subset Viral infection model*
Lung CD4 Influenza [33,51], Coronavirus [35]
CD8 Influenza [28,34,52,53], RSV [54]
Skin CD8 HSV [14,44] VACV [55,56]
FRT CD4 HSV [46]
CD8 HIV [57], HSV [58,59], VACV [9]
Brain CD8 LCMV [31], VSV [30], WNV [60]
Salivary Gland CD8 CMV [61]
*

RSV: respiratory syncytial virus; HSV: Herpes simplex virus; VACV: vaccinia virus; WNV, West Nile virus; VSV: Vesicular stomatitis virus