Table 2:
Multivariable Model Results: Odds Ratios for Nonresponse from the IRIS Registry database
| Categorical Variables | Reference Group | Comparison Group | Odds Ratio | 95% CI for the Estimated Odds Ratio | p-value | |
|---|---|---|---|---|---|---|
| Sex | Male | Female | 1.22 | 1.20 | 1.25 | <0.0001* |
| Sex | Male | Not Recorded | 0.60 | 0.49 | 0.72 | <0.0001* |
| Age Group (years) | 65–79 | 18–39 | 1.29 | 1.17 | 1.42 | <0.0001* |
| Age Group (years) | 65–79 | 40–64 | 1.06 | 1.03 | 1.09 | 0.0001* |
| Age Group (years) | 65–79 | 80+ | 0.93 | 0.91 | 0.96 | <0.0001* |
| Age Group (years) | 65–79 | Not Recorded | 0.97 | 0.83 | 1.14 | 0.7190 |
| Region | South | Midwest | 1.07 | 1.05 | 1.10 | <0.0001* |
| Region | South | Northeast | 1.08 | 1.05 | 1.12 | <0.0001* |
| Region | South | West | 0.92 | 0.82 | 1.04 | 0.7261 |
| Region | South | Unknown | 1.00 | 0.97 | 1.02 | 0.2032 |
| Race | White | Black | 0.91 | 0.85 | 0.98 | <0.0001* |
| Race | White | Asian | 0.94 | 0.91 | 0.97 | 0.0093* |
| Race | White | Multiple Races/Other | 0.96 | 0.92 | 1.00 | 0.9970 |
| Race | White | Hispanic | 1.00 | 0.97 | 1.03 | 0.0616 |
| Race | White | Not Recorded | 0.79 | 0.76 | 0.82 | <0.0001* |
| Insurance | Private | Dual Insurance | 0.93 | 0.89 | 0.96 | 0.0001* |
| Insurance | Private | Medicaid | 0.95 | 0.89 | 1.02 | 0.1866 |
| Insurance | Private | Medicare | 0.90 | 0.86 | 0.93 | 0.0027* |
| Insurance | Private | Medicare | 0.95 | 0.93 | 0.98 | <0.0001* |
| Insurance | Private | Military | 0.88 | 0.78 | 1.00 | 0.0515 |
| Insurance | Private | Other | 0.98 | 0.78 | 1.23 | 0.8660 |
| Insurance | Private | Not Recorded | 1.11 | 1.06 | 1.16 | <0.0001* |
| Provider Specialty | Glaucoma | Cataract | 1.08 | 1.04 | 1.11 | <0.0001* |
| Provider Specialty | Glaucoma | Other | 0.98 | 0.95 | 1.00 | 0.0938 |
| Provider Specialty | Glaucoma | Unknown | 0.91 | 0.78 | 1.06 | 0.2151 |
| Glaucoma Procedure | NO | YES | 1.14 | 1.06 | 1.22 | 0.0004* |
| Lens Surgery | NO | YES | 1.03 | 1.00 | 1.08 | 0.0814 |
| Intravitreal Inj./Surg. | NO | YES | 1.03 | 0.97 | 1.09 | 0.3723 |
| Diabetes | NO | YES | 1.21 | 1.18 | 1.24 | <0.0001* |
| Hypertension | NO | YES | 0.89 | 0.84 | 0.94 | <0.0001* |
| Angle Recession | NO | YES | 2.46 | 1.80 | 3.35 | <0.0001* |
| Uveitis | NO | YES | 1.50 | 1.34 | 1.68 | <0.0001* |
| Provider LTP Count | < 50 | 51–99 | 0.92 | 0.90 | 0.95 | 0.5816 |
| Provider LTP Count | < 50 | 100–499 | 1.19 | 1.13 | 1.25 | <0.0001* |
| Provider LTP Count | < 50 | 500+ | 0.99 | 0.97 | 1.02 | <0.0001* |
| Glaucoma Severity | Mild | Moderate | 0.89 | 0.84 | 0.96 | <0.0001* |
| Glaucoma Severity | Mild | Severe | 1.09 | 1.06 | 1.13 | <0.0001* |
| Glaucoma Severity | Mild | Indeterminate | 0.83 | 0.80 | 0.85 | 0.0010* |
| Glaucoma Severity | Mild | Not Recorded | No odds ratio estimated | |||
| Glaucoma Severity | Mild | Not Applicable | 0.75 | 0.73 | 0.78 | <0.0001* |
| Glaucoma Type | Suspect | POAG | 0.93 | 0.77 | 1.12 | <0.0001* |
| Glaucoma Type | Suspect | Trauma/OED | 0.76 | 0.62 | 0.94 | 0.0005* |
| Glaucoma Type | Suspect | Inflammation/Drugs | 0.91 | 0.88 | 0.94 | 0.4415 |
| Glaucoma Type | Suspect | Other Glaucoma | 1.29 | 1.12 | 1.49 | 0.0105* |
| Glaucoma Type | Suspect | Unspecified Glaucoma | 0.84 | 0.80 | 0.87 | <0.0001* |
| Lens Status | Phakic/Cataract | Pseudophakia | 1.23 | 1.02 | 1.47 | <0.0001* |
| Lens Status | Phakic/Cataract | Aphakia | 1.55 | 1.49 | 1.61 | 0.0259* |
| Lens Status | Phakic/Cataract | Not Recorded | 0.81 | 0.79 | 0.83 | <0.0001* |
| LTP Type | Single | Double | 1.05 | 0.99 | 1.11 | 0.0900 |
| Continuous Variables (increase for odds ratio) | ||||||
| Age at Baseline | 10 year increase in age | 0.74 | 0.71 | 0.78 | <0.0001* | |
| Mean Baseline IOP | 3 mm Hg increase in BL IOP | 0.60 | 0.59 | 0.60 | <0.0001* | |
| Mean BL LogMAR VA | 1 unit increase in LogMAR VA | 1.03 | 1.00 | 1.07 | 0.0617 | |
| Glaucoma Meds | 1 additional glaucoma med cat | 1.04 | 1.03 | 1.05 | <0.0001* | |
Statistically significant p-values are flagged with an asterik
(*).
Possible clinically significant odds ratios are bolded. % = percentage; BL = baseline; cat = categories; CI = confidence interval; Inj. = Injection; IOP = intraocular pressure; IRIS = Intelligent Research in Sight; LogMAR = logarithm of the minimum angle of resolution; LTP = Laser Trabeculoplasty; Meds = medications categories; NPI = National Provider Identifier; OED = Other Eye Disorders; POAG = Primary open angle glaucoma; Surg. = Surgery; VA = visual acuity.