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. Author manuscript; available in PMC: 2022 Mar 18.
Published in final edited form as: Cell Chem Biol. 2021 Mar 1;28(3):257–270. doi: 10.1016/j.chembiol.2021.02.001

Figure 3. Therapeutic applications of HTPS-based discoveries.

Figure 3.

HTPSs can be adapted to include different biological systems including cells, organoid systems, and whole animals. Following the discovery of hit compounds, targets are validated and lead optimization is performed. Optimized compounds can eventually be used for cell-based therapy or be developed into a clinical drug, serving multiple therapeutic purposes.