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. 2021 Feb 24;40(11):2112–2129. doi: 10.1038/s41388-021-01679-8

Fig. 7. USP13 and Mcl-1 expression correlate in cervical cancer.

Fig. 7

A Representative western blot of Mcl-1 expression in normal human keratinocytes (NHKs), C33A, SiHa, CaSKi, SW756 and HeLa cells. GAPDH served as a loading control. B Representative IHC staining of Mcl-1 expression in cervical cancer tissues and normal cervical epithelium from a tissue microarray (TMA). Scale bars, 100 μm. C Scatter dot plot analysis of Mcl-1 expression from a larger cohort of cervical cancer cases (n = 41) and normal cervical epithelium (n = 9) is shown on the right. D Representative IHC staining of USP13 and Mcl-1 expression in cervical cancer tissue from two patients. Staining was performed from separate cores from the same patient samples. Scale bars, 100 μm. Correlation was determined using Spearman’s analysis and is shown on the right. *p < 0.05; **p < 0.01; ***p < 0.001 (Student’s t-test).