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. 2020 Oct 29;70(4):1101–1113. doi: 10.1007/s00262-020-02748-9

Table 1.

Inverse correlation between AURKA expression and T-cell infiltration markers

gene R p value
CD3E − 0.53 0.007
CD4 − 0.50 0.012
CD8A − 0.48 0.019
LCK − 0.52 0.009
PDCD1 − 0.53 0.007
IFNG − 0.43 0.036

The expression of AURKA is significantly inversely correlated with the expression of genes associated with T-cell infiltration of the tumor in a dataset derived from a human melanoma CTLA4 study [14]

R spearman correlation