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. 2021 Jan 22;20(2):733–750. doi: 10.1007/s10237-020-01413-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — LAL causes anatomical changes on embryonic day-5 (ED5) chick hearts 24-h post-surgery. ED5 control and LAL hearts are oriented and H&E processed. a Quantification of length parameters (HH, HW, and MT) in both control and LAL hearts. b The quantification of area parameters (LV, SAVC, and IAVC) in both control and LAL hearts. HH heart height, HW heart width, MT myocardium thickness, LV left ventricle, SAVC superior atrioventricular cushion, IAVC inferior atrioventricular cushion. Data is presented as mean (n = 3), error bars indicate SEM, and p < 0.05 indicates statistical significance as determined by Student’s t test (*p < 0.05)