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. 2020 Oct 17;22(1):125–133. doi: 10.1007/s11154-020-09599-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — All-cause mortality in studies on hypopituitarism with or without growth hormone replacement therapy (GHRT). Data are given as standardized mortality ratios (SMRs) with 95% confidence intervals (CIs) and numbers of observed (Obs.) and expected (Exp.) deaths for studies with GHRT (upper) and without (lower) GHRT. *For Rosen & Bengtsson only the observed and expected number of deaths are given together with the ratio since no confidence interval was presented in this study