Table 1.

Patient characteristics

	Prospective patients	Patients with combination of ablation and surgical resection	Relapsed patients	Patients in long-term remission	p value
	Number (%)	Number (%)	Number (%)	Number (%)
	23	18	13	17
Age median [range, years]	65 [48–83]	70 [41–80]	70 [55–81]	71 [50–87]	0.78
Sex					1.0
Female	7 (30.43%)	7 (38.89%)	2 (15.38%)	3 (17.65%)
Male	16 (69.57%)	11 (61.11%)	11 (84.62%)	14 (82.35%)
Etiology					0.86
Chronic Hepatitis B	2 (8.70%)	4 (22.22%)	2 (15.38%)	5 (29.41%)
Chronic Hepatitis C	7 (30.43%)	5 (27.78%)	3 (23.08%)	2 (11.76%)
Alcohol abuse	3 (13.04%)	3 (16.67%)	2 (15.38%)	2 (11.76%)
Several risk factors	7 (30.43%)	0 (0.00%)	1 (7.69%)	2 (11.76%)
Other	4 (17.39%)	6 (33.33%)	5 (38.46%)	6 (35.29%)
BCLC Stage					0.79
0	1 (4.35%)	0 (0.00%)	0 (0.00%)	0 (0.00%)
A	15 (65.22%)	5 (27.78%)	10 (76.92%)	14 (82.35%)
B	3 (13.04%)	11 (61.11%)	2 (15.38%)	3 (17.65%)
C	4 (17.39%)	2 (11.11%)	1 (7.69%)	0 (0.00%)
D	0 (0.00%)	0 (0.00%)	0 (0.00%)	0 (0.00%)
MELD median [range]	7 [6–14]	7 [6–11]	7.5 [6–17]	7 [6–10]	0.72
Tumor diameter					0.33
< 3 cm	16 (69.57%)	7 (38.89%)	9 (69.23%)	13 (76.47%)
3–5 cm	7 (30.43%)	5 (27.78%)	4 (30.77%)	2 (11.76%)
> 5 cm	0 (0.00%)	6 (33.33%)	0 (0.00%)	2 (11.76%)
Tumor volume median [range, cm3]	3.5 [0.1–30.1]	n.a	2.1 [0.1–14.1]	1.8 [0.1–48.3]	0.44
Ablation:tumor ratio mean	3.3	n.a	3.6	3.5	0.93
Ablation energy median [range, kJ]	50 [24–120]	50.6 [25.2–84]	53.6 [12–122.6]	55.2 [15–90.4]	0.90
Previous treatment					0.29
Local ablative therapy	4 (17.39%)	1 (5.56%)	2 (15.38%)	4 (23.53%)
Surgical resection	3 (13.04%)	4 (22.22%)	2 (15.38%)	1 (5.88%)
TACE/TAE/Radiotherapy	2 (8.70%)	0 (0.00%)	3 (23.08%)	0 (0.00%)
None	14 (60.87%)	13 (72.22%)	6 (46.15%)	12 (70.59%)
AFP					0.36
< 5 [kIU/l]	7 (30.43%)	2 (11.11%)	1 (7.69%)	1 (5.88%)
≥ 5 [kIU/l]	5 (21.74%)	13 (72.22%)	2 (15.38%)	7 (41.18%)
Not determined	11 (47.83%)	3 (16.67%)	10 (76.92%)	9 (52.94%)