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. 2020 Oct 10;20(2):403–431. doi: 10.1007/s10237-020-01391-8

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Evaluation of DICE exemplified with the smallest (a) and the largest head (b), including global structures of the cranial mask (row 1), the brain (row 2), local brain regions of cerebrum GM, WM, cerebellum, hippocampus, thalamus, CC, BS, as well as lateral ventricles. T1W image of the subject is overplayed with the segmented regions from the personalized T1W image (row 3). Enlarged figures show the segmented regions from the personalized T1W image (shown in color) are overlayed with the segmented regions from the subject’s T1W as ground truth (gray), based on which DICE is calculated as exemplified for lateral ventricles, corpus callosum, and thalamus with DICE values shown (row 4)