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. 2021 Mar 19;4:353. doi: 10.1038/s42003-021-01905-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Trend of AMR genotype in 990 Southeast Asian Shigella flexneri and (b) 880 Southeast Asian Shigella sonnei. Each heatmap plot details the resistance trend against a class of antimicrobial, as identified by presence of AMR genetic determinants (see Methods) and categorised into different phylogenetic lineages. The cell’s colour intensity positively correlates to the proportion of sequenced isolates, belonging to a particular lineage during a defined duration, encoding resistance to the examined antimicrobial class (see key). The grey cells denote the absence of sequenced isolates.