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. 2021 Mar 19;11:6428. doi: 10.1038/s41598-021-85760-y

Figure 4.

Figure 4

Circulatory levels of adipose tissue macrophage (ATM) markers in the steady state of obese type 2 diabetes (OT2D). Plasma level of MCP-1 (A), MIF (B) and netrin-1 (C) in control subjects (black circles) and obese subjects with T2D (blue circles). Basal level of plasma MCP-1 did not alter in OT2D compared to control (698 ± 49 vs 760 ± 73 RFU of MCP-1, OT2D vs control, p = ns). Basal level of plasma MIF and netrin-1was increased in OT2D (1387 ± 223 vs 1007 ± 29 RFU of MIF-1 and 558 ± 30 vs 478 ± 19 RFU of netrin-1, OT2D vs control, p < 0.05). Acute normalization of glycemia had no effect on levels of LBP, CD80 or CD38 in T2D subjects (A-C). Data were presented as mean ± SEM. *, p < 0.05.