Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 19;12:1789. doi: 10.1038/s41467-021-22065-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a–c Overexpressing daf-19c with its native promoter increases IFT in the sensory cilia at indicated ages. Representative kymographs, velocities and frequencies are respectively shown in a–c. For a, similar results were obtained in all independent experiments. Horizontal scale bars: 2 μm; vertical scale bars: 2 s. Exact sample size and p value are included in Source Data file. d Overexpressing daf-19c rescues the impaired DiI staining in the aged sensory neurons. Arrows denote the soma. The assay was performed in parallel with Fig. 1b. Scale bar: 10 μm. n = 66, 62, 59, 47, respectively. p = 0.0001(WT day 10 versus WT day 1), 0.026 (daf-19c oe day 1 versus WT day 1), 0.1092 (daf-19c oe day 10 versus daf-19c oe day 1) and 0.0008 (daf-19c oe day 10 versus WT day 10). e Attraction (2-butanone) and repulsion (2-nonanone) chemotaxis assays of indicated strains at day 1 and day 5 of adulthood. n = 4 biological independent experiments. Exact sample size and p value are included in Source Data file. f daf-19c overexpression improves the response to food in the aged worms. Note that a decrease in body bends upon feeding indicates the response to food. n = 4 biological independent experiments. Exact sample size and p value are included in Source Data file. Data are presented as mean ± SEM in b and mean ± SD in the rest. Two-way ANOVA in b, one-way ANOVA in e and unpaired t-test (two-tailed) in the rest, *p < 0.05, **p < 0.01, ***p < 0.001, ns non-significant. Source data with exact p values are provided as a Source Data file.