Table 1.

In vitro efficacy of favipiravir.

Cell line	MOI	Drug effective concentrationa		Infectious titer reductionb
		EC50	EC90	125 µM	250 µM	500 µM
Vero E6	0.001	204 µM	334 µM	2.2	13.2	341.9
	0.01	446 µM	>500 µM	2.0	5.7	10.9
Caco-2	0.001	na	na	5.6	137.4	7720.8
	0.01	na	na	4.0	7.2	144.0

MOI multiplicity of infection, na not applicable.

^aEstimated from dose–response curves of antiviral activity (Supplementary Fig. 1).

^bCalculated using mean infectious titers without favipiravir (virus control).