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. 2021 Mar 19;12(4):298. doi: 10.1038/s41419-021-03558-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A qRT-PCR analysis of upregulated circRNAs expression in ten HPSCC tissues and matched adjacent normal tissue. *p < 0.05. B qRT-PCR analysis of circCUX1 expression in HOK and seven head and neck tumor cell lines. C qRT-PCR analysis of circCUX1 expression in radiosensitive (N = 40) and radioresistant (N = 38) HPSCC tissues and adjacent normal tissue (N = 60). D Kaplan–Meier analysis of overall survival (OS) in HPSCC patients with low vs. high expression of circCUX1. E Kaplan–Meier analysis of disease-free survival in HPSCC patients with low vs. high expression of circCUX1.