Table 1.
Baseline characteristics.
| Characteristic | Group | N = 320 | % |
|---|---|---|---|
| Age, years | <60 | 128 | 40.0 |
| ≥60 | 192 | 60.0 | |
| Sex | Female | 170 | 53.1 |
| Male | 150 | 46.9 | |
| No. of prior therapies | ≤3 | 199 | 62.2 |
| >3 | 121 | 37.8 | |
| Performance status | 0 | 40 | 12.5 |
| 1 | 280 | 87.5 | |
| Platelet count, x 109/L | <140 | 37 | 11.6 |
| 140–440 | 271 | 84.7 | |
| >440 | 12 | 3.8 | |
| No. of metastatic sites | 0–2 | 190 | 59.4 |
| >2 | 130 | 40.6 | |
| Liver metastases | No | 192 | 60.0 |
| Yes | 128 | 40.0 | |
| LDH, IU/L | ≤ULN (618) | 226 | 70.6 |
| >ULN | 77 | 24.1 | |
| UNK | 17 | 5.3 | |
| Albumin, g/dL | <3.5 | 26 | 8.1 |
| ≥3.5 | 294 | 91.9 | |
| Tumor type | Head and neck | 60 | 18.8 |
| Gastrointestinal, other | 52 | 16.3 | |
| Pancreas | 18 | 5.63 | |
| Esophagus | 14 | 4.38 | |
| GEJ | 5 | 1.56 | |
| Liver | 5 | 1.56 | |
| Stomach | 5 | 1.56 | |
| Small intestine | 4 | 1.25 | |
| Bile duct | 1 | 0.31 | |
| Lung | 34 | 10.6 | |
| Colorectal | 29 | 9.1 | |
| Gynecological, other | 30 | 9.4 | |
| Breast | 26 | 8.1 | |
| Sarcoma | 24 | 7.5 | |
| Ovarian | 16 | 5.0 | |
| Genitourinary, other | 14 | 4.4 | |
| Prostate | 11 | 3.4 | |
| Endocrine | 9 | 2.8 | |
| Other | 7 | 2.2 | |
| Bladder | 4 | 1.3 | |
| CUP | 4 | 1.3 |
Abbreviations: CUP cancer of unknown primary, GEJ gastro-esophageal junction, LDH lactate dehydrogenase, No. number, ULN upper limit of normal.