Table 2.
Estimates of false negative rates (FNR) and false discovery rates (FDR) for different structural variant calling methods. Bold numbers highlight the lowest values in each column.
Method | Deletions | Duplications | Inversions | Translocations | All | |||||
---|---|---|---|---|---|---|---|---|---|---|
FNR | FDR | FNR | FDR | FNR | FDR | FNR | FDR | FNR | FDR | |
Illumina + Manta | 0.14 | 0.13 | 0.17 | 0.5 | 0 | 0.29 | 0 | 0.79 | 0.12 | 0.32 |
ONT + Minimap2 + Sniffles | 0.06 | 0.06 | 0 | 0.14 | 0.1 | 0.55 | 0.25 | 0.91 | 0.07 | 0.42 |
ONT + ngmlr + Sniffles | 0.22 | 0.03 | 0 | 0.4 | 0.2 | 0.5 | 0.25 | 0.4 | 0.20 | 0.21 |