Table 1.

Compounds ordered by descending popularity that are one reaction step away from intermediates in the noscapine pathway.

Popularity rank	Name	Best BridgIT score	Predicted EC	Number of citations	Number of patents	Citations + patents
1	Berberine	1.00	1.3.3.8	5430	6751	12154
2	Tetrahydropalmatine	1.00	2.1.1.89	530	355	885
3	Columbamine	0.99	1.3.3.8	131	235	366
4	Salutaridine	1.00	1.14.19.67	85	264	349
5	Norlaudanosoline	0.99	1.14.14.102	144	177	321
6	Stepholidine	0.78	1.14.13.31	157	140	297
7	Allocryptopine	0.32	1.14.13.239	111	159	270
8	Laudanine	1.00	2.1.1.291	23	112	135
9	Codamine	0.79	2.1.1.121	13	61	74
10	Norreticuline	0.09	1.5.3.10	33	40	73
11	Corytuberine	0.56	1.14.19.67	18	39	57
12	Lambertine	0.45	1.3.1.29	30	23	53
13	Armepavine	1.00	2.1.1.291	28	15	43
14	1,2-Dehydroreticuline	1.00	1.5.1.27	3	40	43
15	Nandinine	1.00	1.14.19.73	1	39	40