Sortase-dependent pili |
fimA/P |
Major pilin subunit |
Structural element of sortase-dependent pili. |
fimB/Q |
Minor or ancillary pilin subunit |
strA |
Sortase (transpeptidase enzyme) |
Sortase-dependent pilus assembly and anchoring to the cell surface. |
Tight Adherence pili |
tadA |
ATPase |
|
tadB |
Integral membrane protein |
Formation of hetero- and homo-polymers involved in the secretion apparatus of the pilus subunits. |
tadC |
integral membrane protein |
tadE |
Pseudopilin |
Structural pilus components synthetized as prepilins. |
tadF |
Pseudopilin |
Flp |
Prepilin |
tadV |
Peptidase (enzyme) |
Post-translational processing of prepilins to remove their hydrophobic leader peptide to obtain structural pilus components. |
Quorum sensing |
luxS |
S-ribosylhomocysteine lyase |
It catalyzes the transformation of S-ribosylhomocysteine to homocysteine and 4,5-dihydroxy-2,3-pentadione, the latter known as the precursor of the autoinducer-2 (AI-2). |
sEPS |
Conserved gene set involved in sEPS production |
Priming glycosyl transferase |
It catalyzes the addition of the first saccharidic moiety to a lipophilic carrier molecule for initiation of sEPS repeating unit assembly. |
Glycosyl transferases |
They are involved in the assembly of sEPS repeating units. |
Flippases and/or ABC transporters |
Enzymes involved in the transport of sEPS subunits from the cytoplasm to the outer membrane environment. |
Subunit polymerase |
It catalyzes the polymerization of sEPS subunits. |
Chain length determinant proteins |
They determine the polymer chain length. |
Carbohydrate precursor biosynthesis/modification enzymes |
They catalyze the biosynthesis of sEPS precursor and the conversion of the latter into sEPS subunits. |