Figure 4.

SD-OCT changes following vPDT (group 1). Comparison of SD-OCT changes within, superior to, and inferior to vPDT treatment zone at baseline, at two weeks, and at four weeks after vPDT. Near-infrared (NIR) images are shown adjacent to the corresponding SD-OCT B-scans to indicate the location of the B-scan in relation to the vPDT treatment zone. The boundary of the vPDT treatment zone is highlighted with an interrupted red circle in the NIR image, whereas the B scan location is indicated by the solid horizontal green line. At two and four weeks after vPDT, marked outer retinal changes were observed on SD-OCT (indicated with solid white arrows). These included atrophy of outer retinal layers, severe EZ disruption, and irregular hyperreflective RPE thickening. There were no significant changes observed on SD-OCT outside the vPDT treatment zone.