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Physicochemical properties of lopinavir (LPV) and ritonavir (RTV) nanoparticles (NP) (n = 3).
| LPV NP |
RTV NP |
|||
|---|---|---|---|---|
| Before lyophilization | After lyophilization | Before lyophilization | After lyophilization | |
| Drug Loading (%, w/w) | 8.21 ± 0.08 | 8.13 ± 0.03 | 8.15 ± 0.04 | 8.09 ± 0.08 |
| Encapsulation Efficiency (%) | 99.2 ± 0.14 | 98.9 ± 0.24 | 99.1 ± 0.19 | 98.9 ± 0.17 |
| Zeta Potential (mV) | 32.2 ± 0.5 | 36.9 ± 0.6 | 45.0 ± 0.7 | 47.6 ± 2.6 |
