. 2021 Mar 18;153(4):e202012685. doi: 10.1085/jgp.202012685

Table 6. Properties of quarks, blips, and sparks in a group of 40 RYRs assembled into one, two, or four CRSs of different RYR vicinities.

graphic file with name JGP_202012685_Fig12.jpg

Calculated for i_Ca = 0.25pA. F_q, F_b, F_s are fractions of quarks, blips, and sparks per CRS, respectively. ${\bar{N}}_{O}^{p e a k}$ (spark) indicates the average number of RYRs open at the peak of spark. n_Ca,q, n_Ca,b, and n_Ca,s are the amount of calcium released per average quark, blip, and spark, respectively. the F_x × n_Ca,x indicate the weighted amounts of calcium released by quarks, blips, and sparks in individual scenarios. F_si indicates the fraction of sparks per individual RYRs color-coded according to the color map. ΔF/F₀ is the fluorescence of line scan images for averaged sparks (6 µm vertical × 100 ms horizontal) color coded according to the color map. The white contour lines indicate the detection limit of 0.3 ΔF/F₀ units. Note that the individual CRSs are not spatially resolved.