Skip to main content
. Author manuscript; available in PMC: 2021 Mar 20.
Published in final edited form as: Wiley Interdiscip Rev Syst Biol Med. 2020 Aug 3;13(1):e1503. doi: 10.1002/wsbm.1503

FIGURE 10.

FIGURE 10

(a) A large number of proteins are quantified in every single cells of a biological system. (b) Heterogeneous cells are partitioned into different subgroups, with each subgroup consisting of cells possessing similar protein expression profiles. (c) Specific cell neighborhoods with unique cell subgroup compositions are identified. (d) Pairwise protein expression correlation analysis is carried out with each spot presenting one cell and its protein expression levels shown in x and y axes. (e) A regulatory network is generated with activating and inhibitory interactions