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. 2021 Feb 5;206(7):1569–1575. doi: 10.4049/jimmunol.2001126

Table III. Logistic regression models evaluating 28-d survival.


Univariate
Multivariate (Model A)a
Multivariate (Model B)b
OR 95% CI OR 95% CI OR 95% CI
Gender, males versus females 0.67 0.27–1.79
Oxygen support, CPAP versus intubation 0.46 0.17–1.30
Age, per 1 y more 0.87 0.82–0.93 0.88 0.81–0.95
P/F, per 10 mm Hg higher 1.21 1.08–1.36 1.20 1.05–1.37
CCI, per 1 point higher 0.46 0.32–0.64 0.55 0.31–0.98
Hypertension 0.37 0.17–0.82 0.98 0.32–3.16
Ischemic heart disease 0.35 0.13–0.95 0.67 1.16–2.79
COPD 1.042 0.24–4.60
Diabetes mellitus 0.94 0.54–1.73
Obesity/overweight (BMI >25 kg/m2) 2.13 0.96–4.71
Anakinra use 3.20 1.47–7.17 2.46 0.87–7.00 5.61 1.75–10.01
CRP, per mg/dl higher 0.97 0.93–1.02 0.99 0.94–1.04
D-dimer, per 100 ng/ml higher 0.98 0.96–1.01 0.99 0.97–1.01
Lymphocytes, per 1000 cells/mm3 higher 0.48 0.18–1.29
Ferritin, per 100 ng/ml higher 1.03 0.98–1-08
Symptom duration before hospitalization, per 1 d higher 1.05 0.96–1.14
a

Model A included all correlates that were significantly associated with survival in the univariate model.

b

Model B included all the correlates that were differently distributed at baseline in the two study groups (i.e., CRP and d-dimer).

BMI, body mass index; CCI, Charlson comorbidity index; COPD, chronic obstructive pulmonary disease; P/F, partial pressure of oxygen in arterial blood to fractional concentration of oxygen.